3 Ways to Manage OxyContin Withdrawal Symptoms With Professional Support

October 16, 2025

3 Ways to Manage OxyContin Withdrawal Symptoms With Professional Support

October 16, 2025

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No matter what brought you to this point today, you don’t have to go through it by yourself. Professional, compassionate support for OxyContin withdrawal symptoms is available. ReKlame Health can provide professional virtual treatment for you (or a loved one) going through withdrawal symptoms like restlessness, nausea, anxiety or pain. Here, we will provide a basic road map for what’s ahead. It is an uncomfortable one, but you may find that the destination’s focus, stability and empowerment are worth it. You can learn more about establishing care with ReKlame in our FAQ.

Find out about withdrawal symptoms

OxyContin, or oxycodone, has both short-acting and long-acting formulations. Because of this, the time period between your last dose and your first withdrawal symptoms may vary.

Discontinuing short-acting OxyContin may cause symptoms in eight to 24 hours. If you quit using long-acting OxyContin, you may go as long as 36 hours without experiencing symptoms. Additionally, any medications or substances you use may affect your experience in withdrawal.

Early OxyContin withdrawal symptoms

At first, you might feel a hard-to-pin-down feeling of discomfort called malaise. Your eyes and nose might run, and you might feel sweaty, achy and tired, as if you were coming down with the flu.

However, when you want to rest, sleep might not come. Insomnia could be accompanied by restlessness, muscle twitching and yawning. You may have goosebumps or dilated pupils. Taking an opioid to escape withdrawal symptoms may be tempting.

Later withdrawal symptoms

As you move past the early withdrawal symptoms, you might lose your appetite, feel nauseated, vomit or have diarrhea. This can cause dehydration.

You might have high blood pressure, high blood sugar or a rapid heart rate (tachycardia). You may also find yourself breathing quickly. The restlessness that may have emerged earlier can worsen and anxiety can develop. You may have a strong craving for OxyContin or anything to ease these symptoms, but it’s important to resist it.

Explore options for symptom management

ReKlame offers medication-assisted treatment (MAT). You can learn what sets us apart from others here. If you work with one of our virtual care teams, we can create a treatment plan designed to ease your withdrawal symptoms. This may make quitting opioids less disruptive to your life and easier to maintain, opening the door to further recovery. We can also treat concurrent addictions or dependencies like alcohol use disorder.

A psychiatric nurse practitioner can offer:

Buprenorphine

This medication is a partial opioid agonist, which means that it can reduce OxyContin withdrawal symptoms and cravings without producing a euphoric experience. Using buprenorphine may allow you to participate in treatment without disruptive, uncomfortable symptoms.

Suboxone

Suboxone is a brand name for a combination of buprenorphine and naloxone. Naloxone, sold on its own as Narcan, is well known as an emergency treatment for opioid overdose. It has an additional use: preventing people in recovery from using opioids again by altering their response. It removes the pleasurable reaction to opioids. If you’re taking Suboxone, buprenorphine will treat your withdrawal symptoms while naloxone prevents repeat drug use.

Naltrexone

This opioid addiction treatment medication, which is also used to treat alcohol addiction, is an opioid antagonist. It is used to help people who have already quit using opioids maintain their recovery. This medication blocks the effects of opioids. 

One of these medications may be the cornerstone of MAT for you, but you may have symptoms that require additional treatment. For aches and pain, we may recommend over-the-counter medications like NSAIDs. We may prescribe non-opioid prescription medication without a risk of misuse. You can also ask a treatment provider about over-the-counter or prescribed solutions to other common problems, like insomnia, nausea, diarrhea or muscle spasms.

ReKlame can support your mental health

Our professionals offer holistic, culturally competent care for a variety of mental health conditions. Our approach is rooted in harm reduction. If you are living with a substance use disorder, you may be one of approximately 21.5 American adults with a co-occurring disorder.

Some of the most common are ADHD, PTSD, anxiety, major depression, bipolar disorder, schizophrenia and conduct disorders. You don’t have to face any of these issues by yourself. Our team can provide psychiatric medication management and a care navigator to help you find and maintain better mental health in long-term recovery.

Give our care team a call today for more information, check your eligibility for free online or book an initial appointment online.

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